Plasma cell-rich lesions in the oral cavity

an overview and case presentation

Autores

  • Ana Paula Negreiros Nunes Alves Universidade Federal do Ceará
  • Mário Rogério Lima Mota Universidade Federal do Ceará
  • Fabrício Bitu Sousa Universidade Federal do Ceará
  • Karuza Maria Alves Pereira Universidade Federal do Ceará
  • Guilherme Costa Soares
  • Erick Helton Lima Fontenele Unichristus
  • Dalgimar Beserra de Menezes Universidade Federal do Ceará

DOI:

https://doi.org/10.59483/rfpp.v3n4.97

Palavras-chave:

Células plasmáticas, Sífilis oral, Mucosite de células plasmáticas, Plasmocitoma

Resumo

The oral mucosa and gnathic bones can be targets of different types of diseases, however, some of them have plasma cell infiltrate as the main histopathological feature including reactive lesions, oral infectious disease, or a true neoplasm. It is important to examine the clonality of the seconditionstodemonstrate a polyclonalor monoclonal proliferation, beingthelast a findingthatis more consistentwith a neoplasticprocess. Here, wepresent four cases reportsof oral plasma celllesions, including Plasmacellmucositis (reactionalinflammatoryorigin), Syphilis (infectiouslesion) andtwo cases ofSolitaryPlasmacytoma/MultipleMyeloma (neoplasticlesion). Resultsfromthemicroscopiccharacteristicsassociatedwithimmunohistochemicalanalysessupportedthe final diagnosiseachofthem. The patientswithPlasmcellmucositisandSyphilisweretreatedsucessfully. The twofemalepatientswithPlasmocytomaextramedullarywerereferred for chemotherapytreatment.

Biografia do Autor

Ana Paula Negreiros Nunes Alves, Universidade Federal do Ceará

Full Professor of Oral Pathology of the Dentistry Course at the Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará

Mário Rogério Lima Mota, Universidade Federal do Ceará

bAssociate Professor of Oral Pathology and Stomalogy of the Dentistry Course at the Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará,

Fabrício Bitu Sousa, Universidade Federal do Ceará

bAssociate Professor of Oral Pathology and Stomalogy of the Dentistry Course at the Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará

Karuza Maria Alves Pereira, Universidade Federal do Ceará

cAssociate Professor of Histology at the Medicine Course, Federal University of Ceará

Guilherme Costa Soares

Master by the Posgraduate Program in Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará

Erick Helton Lima Fontenele, Unichristus

Master Student of the Dentstry Posgraduate Program in Unichristus, Fortaleza, Ceará

Dalgimar Beserra de Menezes, Universidade Federal do Ceará

Lecturer in Pathological Anatomy at the Medicine Course, State University of Ceará. Emeritus Professor at the Medicine Course, Federal University of Ceará

Referências

Hilgert R, Fonseca LAM, Ribeiro FF, Soares LY. Plasmocitoma solitário em mandíbula: relato de caso. Revista de Cirurgia e Traumatologia Buco-maxilo-facial, 2012; 12(3):67-72.

Cicinelli E, Haimovich S, De Ziegler D, Raz N, Ben-Tzur D, Andrisani A, et al. MUM-1 immunohistochemistry has high accuracy and reliability in the diagnosis of chronic endometritis: a multi-centre comparative study with CD-138 immunostaining. J Assist Reprod Genet. 2021; 39(1):219-226.

SolomonLW, WeinRO, RosenwaldI, LaverN. Plasma cell mucositis of the oral cavity: report of a case and review of the literature. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2008; 106(6), 853-860.

Puvanendran M, Lieder A, Issing W. Plasma cell mucositis of oro-and hypopharynx: a case report. Case Reports in Otolaryngology. 2012

Jo VY. Soft Tissue Special Issue: Myoepithelial Neoplasms of Soft Tissue: An Updated Review with Emphasis on Diagnostic Considerations in the Head and Neck. Head Neck Pathol. 2020; 14(1):121-131.

Agaimy A, Hartmann A, Antonescu CR, Chiosea SI, El-Mofty SK, Geddert H, et al. SMARCB1 (INI-1)-deficient Sinonasal Carcinoma: A Series of 39 Cases Expanding the Morphological and Clinicopathological Spectrum of a Recently Described Entity. Am J Surg Pathol. 2017; 41(4):458–471.

Kocovski L, Bane A, Tang S, Salama S, Alowami S. Amelanotic Melanoma Presenting with Plasmacytoid Morphology and BRAF V600 Mutation. Rare tumors. 2015; 7(2):5698.

Smith JGF, Smith CP, Leyden PJ. Plasma cell mucositis of the larynx. Clinical case reports. 2018; 6(9):1761.

Triplett J, Hee G, McLean-Tooke A, Lucas M. Long-term control of laryngeal plasma cell mucositis with systemic immunosuppression. Case Reports. 2018; 2018:bcr-2017-221333.

Gasparro R, Adamo D, Masucci M, Sammartino G, Mignogna MD. Use of injectable platelet‐rich fibrin in the treatment of plasma cell mucositis of the oral cavity refractory to corticosteroid therapy: A case report. Dermatologic therapy. 2019; 32(5):e13062.

Micucci SB, Zim SA, Hosfield EM. Plasma Cell Mucositis of the Hard Palate. Ear, Nose & Throat Journal. 2019; 0145561319872732.

Shanahan D, Shipley D, Staines K. Plasma cell mucositis. Ear, Nose & Throat Journal. 2020; 99(6):NP64-NP65.

Seoane J, Aguirre J, Esparza G, Suárez M, Campos J, Pomareda M. Espectro de las neoplasias de células plasmáticas enelámbito de lapatologíamaxilofacial. Med Oral. 2003; 8:269-80.

Marotta S, Di Micco P. Solitaryplasmacytomaofthejaw. Journal of blood medicine. 2010; 1:33.

Kucukkurt S, Karan NB, Senguven B, Kahraman S. Solitary plasmacytoma of the mandible: report of two cases. Case Reports. 2016; 2016.

Lombardo EM, Maito FLDM, Heitz C. Solitaryplasmacytomaofthejaws: therapeuticalconsiderationsandprognosisbasedon a case reportssystematicsurvey. BrazilianJournalofOtorhinolaryngology. 2018; 84(6): 790-798.

Tsang RW, Campbell BA, Goda JS, Kelsey CR, Kirova YM, Parikh RR, et al. Radiation therapy for solitary plasmacytoma and multiple myeloma: Guidelines from the International Lymphoma Radiation Oncology Group. International Journal of Radiation Oncology* Biology* Physics. 2018; 101(4):794-808.

Pham A, Mahindra A. Solitary plasmacytoma: a review of diagnosis and management. Current hematologic malignancy reports. 2019; 14(2):63-69.

Leuci S, Martina S, Adamo D, Ruoppo E, Santarelli A, Sorrentino R, et al. Oral syphilis: a retrospective analysis of 12 cases and a review of the literature. Oral diseases. 2013; 19(8):738-746.

Hertel M, Matter D, Schmidt-Westhausen AM, Bornstein MM. Oral syphilis: a series of 5 cases. Journal of oral and maxillofacial surgery. 2014; 72(2):338-345.

Strieder LR, León JE, Carvalho YR, Kaminagakura E. Oral syphilis: reportofthree cases andcharacterizationoftheinflammatorycells. AnnalsofDiagnosticPathology. 2015; 19(2):76-80.

Araujo JP, Jaguar GC, Alves FA. Syphilisrelatedtoatypical oral lesionsaffectinganelderly man. A case report. Gerodontology. 2015; 32(1):73-75.

Pires FR, Da Silva PJS, Natal RF, Alves FA, Pinto CAL, Rumayor A, et al. Clinicopathologicfeatures, microvesseldensity, andimmunohistochemicalexpressionof ICAM-1 and VEGF in 15 cases ofsecondarysyphiliswith oral manifestations. Oral Surgery, Oral Medicine, Oral Pathologyand Oral Radiology. 2016; 121(3):274-281.

Schuch LF, Da Silva KD, De Arruda JAA, Etges A, Gomes APN, Mesquita RA, et al. Forty cases of acquired oral syphilis and a review of the literature. International Journal of Oral and Maxillofacial Surgery. 2019; 48(5):635-643.

Thompson LDR. Oral Syphilis. Ear, Nose & Throat Journal. 2019: 0145561319890154.

Porterfield C, Brodell D, Dolohanty L, Scott G. Primary Syphilis Presenting As a Chronic Lip Ulcer. Cureus. 2020; 12(2).

Matias MDP, Jesus AO, Resende RG, Caldeira PC, Aguiar MCF. Diagnosing acquired syphilis through oral lesions: the 12 year experience of an Oral Medicine Center. Brazilian journal of otorhinolaryngology. 2020; 86(3):358-363.

Downloads

Publicado

20-12-2023

Como Citar

1.
Alves APNN, Mota MRL, Sousa FB, Pereira KMA, Soares GC, Fontenele EHL, Menezes DB de. Plasma cell-rich lesions in the oral cavity: an overview and case presentation. RFPP [Internet]. 20º de dezembro de 2023 [citado 21º de novembro de 2024];3(4). Disponível em: https://revistadeodontologia.facpp.edu.br/index.php/rfpp/article/view/97

Edição

v. 3 n. 4 (2023)

Seção

Artigos

Licença

Copyright (c) 2023 Licença Creative Commons Attribution-ShareAlike 4.0 International License. Esta licença permite que outros remixem, ajustem e desenvolvam seu trabalho de forma não comercial, desde que creditem a autoria e licenciem suas novas criações sob os mesmos termos.

Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution-ShareAlike 4.0 International License.

Esta licença permite que outros remixem, ajustem e desenvolvam seu trabalho de forma não comercial, desde que creditem a autoria e licenciem suas novas criações sob os mesmos termos.

Artigos mais lidos pelo mesmo(s) autor(es)